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Gluten-Free Seafood Nachos

April 29, 2018 (Last Updated: July 14, 2026)
Italian Fusion Seafood Nachos

These gluten-free seafood nachos are a fresh, healthy twist on a classic favorite. Crispy gluten-free tortilla chips are layered with a garlicky seafood medley, aged cheese, creamy avocado, olives, radishes, scallions, and fresh cilantro, then finished with a tangy yogurt sauce and a squeeze of fresh lime. It’s an unexpected combination that just works — light yet satisfying, packed with contrasting textures and bright flavors, and perfect for sharing as an appetizer, casual dinner, or weekend sharing platter.

Homemade Gluten-Free Tortilla Chips

You can make this recipe with your favorite gluten-free tortilla chips, but I love making my own from almond flour or cassava flour tortillas. Simply cut the tortillas into wedges and bake them for about 5 minutes until crisp.

Almond flour tortillas make a delicious lower-carb option, while cassava tortillas are a great nut-free alternative. If you’re short on time, good-quality store-bought gluten-free tortilla chips work just as well.

A baking dish with gluten-free tortilla chips.
A baking dish with the fresh seafood spread over the tortilla chips.
Seafood nachos

The Seafood Medley

Frozen seafood medleys make this recipe incredibly easy. You’ll usually find them in the frozen seafood section of larger supermarkets, where they often include a combination of shrimp, calamari, mussels, clams, octopus, scallops, or pieces of white fish.

I used a wild-caught seafood medley with shrimp, clams, calamari, white fish, mussels, and octopus, but almost any combination will work.

If you can’t find a seafood medley, simply combine about 1 pound (450 g) of your favorite seafood. Shrimp, calamari, mussels, scallops, clams, or chunks of firm white fish are all great choices.

The baked seafood nachos.
Serving a nacho.

Fresh Toppings Make the Difference

The warm seafood and crispy chips pair beautifully with cool, fresh toppings. Creamy avocado, peppery radishes, scallions, cilantro, olives, and freshly grated Pecorino Romano add plenty of flavor, texture, and color.

Instead of a heavy cheese sauce, I make a quick yogurt sauce using the flavorful juices left in the pan after cooking the seafood. It adds just enough creaminess while letting the seafood remain the star of the dish.

Warm seafood and crispy chips.
Seafood nachos with shrimps and mussels.

Enjoy!

*This post contains affiliated links, which means I get a small commission if you choose to purchase something via one of my links, at no extra cost to you.

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Italian Fusion Seafood Nachos

Gluten-Free Seafood Nachos

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  • Author: Claudia Curici, Health Coach
  • Prep Time: 30 minutes
  • Cook Time: 20 minutes
  • Total Time: 50 minutes
  • Yield: 4
  • Category: Dinner
  • Method: Baking
  • Diet: Gluten-Free

Description

These gluten-free seafood nachos are a fresh, healthy twist on a classic favorite. Crispy gluten-free tortilla chips are layered with a garlicky seafood medley, aged cheese, creamy avocado, olives, radishes, scallions, and fresh cilantro, then finished with a tangy yogurt sauce and a squeeze of fresh lime. It’s an unexpected combination that just works — light yet satisfying, packed with contrasting textures and bright flavors, and perfect for sharing as an appetizer, casual dinner, or weekend sharing platter.


Ingredients

For the chips

  • 6 Siete Almond Flour Tortillas (or any gluten-free tortillas or tortilla chips)
  • 1/41/2 cup grated Pecorino Romano

For the seafood

  • 1 pound seafood medley (frozen or fresh)
  • 1 organic lemon (juice and zest)
  • 2 large garlic cloves, smashed
  • 1 tablespoon extra virgin olive oil
  • Salt and freshly ground black pepper

For the sauce

  • 1/4 cup goat yogurt (or organic grass-fed/Jersey sour cream)
  • Reserved pan juices from the seafood
  • Extra virgin olive oil, if needed
  • Pinch of cumin
  • Pinch of oregano
  • Salt and pepper
  • Sriracha, to taste (optional)

For the toppings

  • 1 bunch cilantro
  • 1 avocado
  • 1 small bunch scallions
  • 1/2 cup pitted olives (I used dry-cured Beldi olives)
  • 4 medium red radishes
  • 1 lime, cut into wedges


Instructions

  1. Preheat the oven to 350°F (180°C).
  2. Prepare the toppings by washing, drying, and chopping the cilantro, scallions, radishes, avocado, and lime.
  3. If making homemade chips, cut the tortillas into triangles and bake them for about 5 minutes, until crisp. Work in two batches if needed.
  4. Heat the olive oil in a large skillet over medium heat. Add the smashed garlic and cook for about 2 minutes, until fragrant.
  5. Add the seafood, lemon juice, lemon zest, salt, and pepper. Cook for just a few minutes, then transfer the seafood to a bowl, leaving the flavorful juices in the pan.
  6. Stir the goat yogurt, reserved pan juices, a drizzle of olive oil (if needed), cumin, oregano, salt, pepper, and sriracha together to make the sauce. Taste and adjust the seasoning.
  7. Arrange the tortilla chips on a parchment-lined baking sheet. Sprinkle with the Pecorino Romano, then layer on the seafood, olives, avocado, radishes, scallions, and cilantro. Reserve a little cilantro and scallions for serving.
  8. Drizzle some of the sauce over the nachos and bake for 10 minutes.
  9. Remove from the oven, garnish with the remaining cilantro and scallions, and serve immediately with the remaining sauce and fresh lime wedges.

Notes

Make your own seafood mix. If you can’t find a frozen seafood medley, combine about 1 pound (450 g) of shrimp, calamari, mussels, scallops, clams, or firm white fish.

Don’t overcook the seafood. It only needs a quick sauté before finishing in the oven.

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